Amlodipine + Telmisartan
Find more information about this combination medication at the webpages for amlodipine and telmisartan
Hypertension, Variant Angina Pectoris ... show more
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Advisory
- This medicine contains a combination of 2 drugs amlodipine and telmisartan.
- amlodipine and telmisartan are both used to treat the same disease or symptom but work in different ways in the body.
- Most doctors will advise making sure that each individual medicine is safe and effective before using a combination form.
Drug Status
Government Approvals
None
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Angiotensin 2 Receptor Blocker and Calcium Channel Blocker and Dihydropyridine Calcium Channel Blocker
Controlled Drug Substance
NO
amlodipine + telmisartan
Summary
Amlodipine and telmisartan are used to treat high blood pressure, which is also known as hypertension. By lowering blood pressure, they help reduce the risk of serious complications like heart attacks, strokes, and kidney problems. Amlodipine is also used to treat chest pain, known as angina, by improving blood flow to the heart. Both medicines work together to manage blood pressure effectively and improve overall cardiovascular health.
Amlodipine works by blocking calcium channels in the blood vessels, which relaxes and widens them, making it easier for blood to flow and reducing blood pressure. Telmisartan blocks the action of a hormone called angiotensin II, which normally tightens blood vessels. By blocking this hormone, telmisartan helps to relax and widen the blood vessels, lowering blood pressure. Both medicines work together to improve blood flow and reduce the heart's workload, effectively managing high blood pressure and reducing the risk of cardiovascular events.
The usual adult dose for amlodipine is 5 to 10 mg once daily, depending on the individual's response and medical condition. For telmisartan, the typical dose is 20 to 80 mg once daily. The exact dose may vary based on the patient's needs and the doctor's prescription. Both medicines are taken orally and can be adjusted by the healthcare provider to achieve optimal blood pressure control. It's important to follow the prescribed dosage and not to adjust the dose without consulting a healthcare provider.
Common side effects of amlodipine include swelling of the ankles or feet, dizziness, and flushing, which refers to a warm, red feeling in the face. Telmisartan may cause dizziness, fatigue, and back pain. Both medicines can cause low blood pressure, which might lead to fainting or lightheadedness. Significant adverse effects, though rare, include severe allergic reactions, liver problems, or changes in kidney function. It's important to monitor for these effects and consult a healthcare provider if they occur.
Amlodipine should be used cautiously in patients with severe heart conditions, such as heart failure, due to the risk of worsening symptoms. Telmisartan is contraindicated in pregnancy and should not be used by individuals with severe liver or kidney problems. Both medicines can cause low blood pressure, so patients should be cautious when standing up quickly. It's important to avoid using telmisartan with potassium supplements or salt substitutes containing potassium. Patients should inform their healthcare provider of any existing health conditions or medications to avoid potential risks.
Indications and Purpose
How does combination of amlodipine and telmisartan work?
Amlodipine works by blocking calcium channels in the blood vessels, which relaxes and widens them, making it easier for blood to flow and reducing blood pressure. Telmisartan blocks the action of a hormone called angiotensin II, which normally tightens blood vessels. By blocking this hormone, telmisartan helps to relax and widen the blood vessels, lowering blood pressure. Both medicines work together to improve blood flow and reduce the heart's workload, effectively managing high blood pressure and reducing the risk of cardiovascular events.
How does combination of Amlodipine and Telmisartan work?
Amlodipine works by blocking calcium channels in the blood vessels, leading to relaxation and dilation, which reduces blood pressure. Telmisartan blocks the action of angiotensin II, a substance that causes blood vessels to tighten, thereby allowing blood to flow more smoothly and reducing blood pressure. Both medications aim to lower blood pressure but do so through different mechanisms, providing a complementary effect that enhances overall cardiovascular protection.
How effective is combination of amlodipine and telmisartan?
Clinical studies have shown that amlodipine effectively lowers blood pressure by relaxing blood vessels, which reduces the heart's workload. Telmisartan has been proven to block the action of certain chemicals that cause blood vessels to tighten, thus lowering blood pressure. When used together, these medicines provide a complementary effect, enhancing blood pressure control more than either medicine alone. The combination has been shown to reduce the risk of cardiovascular events, such as heart attacks and strokes, by maintaining consistent blood pressure levels. Both medicines are well-studied and widely used for hypertension management.
How effective is combination of Amlodipine and Telmisartan?
Clinical trials have demonstrated that Amlodipine and Telmisartan effectively lower blood pressure and reduce the risk of cardiovascular events. Amlodipine has been shown to improve blood flow and reduce angina symptoms, while Telmisartan has been proven to decrease the likelihood of heart attacks and strokes in high-risk patients. Both medications have been tested in various populations and have consistently shown to be effective in managing hypertension, providing a comprehensive approach to cardiovascular health.
Directions for Use
What is the usual dose of combination of amlodipine and telmisartan?
The usual adult dose for amlodipine is 5 to 10 mg once daily, depending on the individual's response and medical condition. For telmisartan, the typical dose is 20 to 80 mg once daily. The exact dose may vary based on the patient's needs and the doctor's prescription. Both medicines are taken orally and can be adjusted by the healthcare provider to achieve optimal blood pressure control. It's important to follow the prescribed dosage and not to adjust the dose without consulting a healthcare provider.
What is the usual dose of combination of Amlodipine and Telmisartan?
The usual dose of the combination of Amlodipine and Telmisartan can vary based on individual health needs, but a common starting dose is 5 mg of Amlodipine and 40 mg of Telmisartan once daily. The dose may be adjusted by a healthcare provider depending on the patient's response and blood pressure goals. It's important to follow the specific dosing instructions provided by a healthcare professional.
How does one take combination of amlodipine and telmisartan?
Amlodipine and telmisartan can be taken with or without food, making them convenient for daily use. It's important to take them at the same time each day to maintain consistent blood levels. While there are no specific food restrictions, it's advisable to avoid grapefruit juice with amlodipine, as it can increase the medicine's levels in the blood. Patients should follow their healthcare provider's instructions and report any unusual symptoms or side effects.
How does one take combination of Amlodipine and Telmisartan?
Amlodipine and Telmisartan can be taken with or without food, making them convenient for daily use. It is important to take them at the same time each day to maintain consistent blood levels. Patients should follow any specific dietary instructions provided by their doctor, such as a low-salt diet, to enhance the effectiveness of the medication. There are no specific food restrictions, but patients should avoid using potassium supplements or salt substitutes containing potassium without consulting their doctor.
For how long is combination of amlodipine and telmisartan taken?
Amlodipine and telmisartan are typically used as long-term treatments for high blood pressure. The duration of use depends on the individual's response and the healthcare provider's recommendations. These medicines are often taken for many years to maintain blood pressure control and prevent complications. Regular follow-up appointments with a healthcare provider are important to monitor effectiveness and make any necessary adjustments to the treatment plan.
For how long is combination of Amlodipine and Telmisartan taken?
Amlodipine and Telmisartan are typically used as long-term treatments for managing high blood pressure. Both medications are intended for continuous use to maintain blood pressure control and prevent complications such as heart disease and stroke. While they do not cure hypertension, they help manage the condition effectively when taken regularly. Patients are advised to continue taking these medications even if they feel well, as stopping them can lead to a return of high blood pressure.
How long does it take for combination of amlodipine and telmisartan to work?
Amlodipine, which is a calcium channel blocker, usually starts working within 24 to 48 hours to lower blood pressure. Telmisartan, which is an angiotensin receptor blocker, may take a few weeks to show its full effect, although some initial effects can be seen within a few hours. Together, these medicines work to relax blood vessels, which helps to lower blood pressure more effectively. The combination may provide a quicker onset of action due to amlodipine, while telmisartan contributes to sustained blood pressure control over time.
How long does it take for combination of Amlodipine and Telmisartan to work?
Amlodipine and Telmisartan, when used together, typically start to show effects within a few hours. Amlodipine, a calcium channel blocker, begins to work by relaxing blood vessels, which can lead to a reduction in blood pressure within 6 to 12 hours. Telmisartan, an angiotensin II receptor blocker, also starts to lower blood pressure within 3 hours after the first dose. Both medications work to reduce blood pressure, but they do so through different mechanisms, which can complement each other and provide a more comprehensive approach to managing hypertension.
Warnings and Precautions
Are there harms and risks from taking combination of amlodipine and telmisartan?
Common side effects of amlodipine include swelling of the ankles or feet, dizziness, and flushing, which refers to a warm, red feeling in the face. Telmisartan may cause dizziness, fatigue, and back pain. Both medicines can cause low blood pressure, which might lead to fainting or lightheadedness. Significant adverse effects, though rare, include severe allergic reactions, liver problems, or changes in kidney function. It's important to monitor for these effects and consult a healthcare provider if they occur. Both medicines share the potential for causing dizziness, especially when starting treatment or adjusting doses.
Are there harms and risks from taking combination of Amlodipine and Telmisartan?
Common side effects of Amlodipine include swelling of the hands, feet, or ankles, dizziness, and flushing. Telmisartan may cause back pain, sinus pain, and diarrhea. Both medications can lead to dizziness or lightheadedness, especially when starting treatment. Serious adverse effects, though rare, include severe allergic reactions, rapid heartbeat, and significant drops in blood pressure. Patients should report any severe or persistent side effects to their healthcare provider.
Can I take combination of amlodipine and telmisartan with other prescription drugs?
Amlodipine can interact with other blood pressure medications, leading to an excessive drop in blood pressure. It may also interact with certain heart medications, like beta-blockers, which can enhance its effects. Telmisartan can interact with diuretics, which are water pills, and other medications that affect potassium levels, increasing the risk of high potassium. Both medicines can interact with NSAIDs, which might reduce their effectiveness. It's important to inform healthcare providers about all medications being taken to avoid interactions. Regular monitoring and possible dose adjustments may be necessary.
Can I take combination of Amlodipine and Telmisartan with other prescription drugs?
Amlodipine can interact with other blood pressure medications, increasing the risk of low blood pressure. Telmisartan should not be used with aliskiren in patients with diabetes due to the risk of kidney problems. Both medications can interact with NSAIDs, potentially reducing their effectiveness and affecting kidney function. Patients should inform their healthcare provider of all medications they are taking to avoid adverse interactions.
Can I take combination of amlodipine and telmisartan if I am pregnant?
Amlodipine is generally not recommended during pregnancy unless absolutely necessary, as its safety has not been fully established. Telmisartan is contraindicated during pregnancy, especially in the second and third trimesters, due to the risk of harm to the developing fetus, including kidney damage and decreased amniotic fluid. Both medicines should be avoided during pregnancy, and alternative treatments should be considered. If a patient becomes pregnant while taking these medicines, they should contact their healthcare provider immediately to discuss safer options.
Can I take combination of Amlodipine and Telmisartan if I am pregnant?
Amlodipine and Telmisartan are not recommended during pregnancy, especially in the second and third trimesters, due to the risk of fetal harm. Telmisartan can cause injury or death to the developing fetus by affecting kidney function and blood pressure regulation. Amlodipine's safety in pregnancy is not well established, and it should only be used if no safer alternatives are available. Pregnant women should discuss their treatment options with their healthcare provider to ensure the safety of both mother and child.
Can I take combination of amlodipine and telmisartan while breastfeeding?
Amlodipine is considered to be relatively safe during breastfeeding, as only small amounts are expected to pass into breast milk. However, caution is advised, and monitoring the infant for any side effects is recommended. Telmisartan's safety during breastfeeding is not well established, and it is generally advised to avoid its use due to the potential for adverse effects on the nursing infant. Both medicines require careful consideration and consultation with a healthcare provider to weigh the benefits and risks when breastfeeding. Alternative medications may be recommended.
Can I take combination of Amlodipine and Telmisartan while breastfeeding?
The safety of Amlodipine and Telmisartan during lactation is not well established. Amlodipine is known to be excreted in human milk, but the effects on the nursing infant are unknown. It is not clear if Telmisartan is excreted in human milk, but it is present in the milk of lactating animals. Due to potential risks, breastfeeding mothers should consult their healthcare provider to weigh the benefits and risks of continuing these medications while nursing.
Who should avoid taking combination of amlodipine and telmisartan?
Amlodipine should be used cautiously in patients with severe heart conditions, such as heart failure, due to the risk of worsening symptoms. Telmisartan is contraindicated in pregnancy and should not be used by individuals with severe liver or kidney problems. Both medicines can cause low blood pressure, so patients should be cautious when standing up quickly. It's important to avoid using telmisartan with potassium supplements or salt substitutes containing potassium. Patients should inform their healthcare provider of any existing health conditions or medications to avoid potential risks.
Who should avoid taking combination of Amlodipine and Telmisartan?
Amlodipine and Telmisartan should not be used during pregnancy due to the risk of harm to the fetus. Patients with severe liver or kidney impairment should use these medications with caution. Both drugs can cause dizziness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them. It's important to monitor for signs of low blood pressure, especially when starting treatment or adjusting doses.
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